ATP-Sensitive Potassium Channel-Deficient Mice Show Hyperphagia but Are Resistant to Obesity

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ATP-Sensitive Potassium Channel-Deficient Mice Show Hyperphagia but Are Resistant to Obesity

BACKGROUND The hypothalamus, the center for body weight regulation, can sense changes in blood glucose level based on ATP-sensitive potassium (K(ATP)) channels in the hypothalamic neurons. We hypothesized that a lack of glucose sensing in the hypothalamus affects the regulations of appetite and body weight. METHODS To evaluate this hypothesis, the responses to glucose loading and high fat fee...

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ATP-sensitive Potassium Channels and L-type Calcium Channels are Involved in Morphine-induced Hyperalgesia after Nociceptive Sensitization in Mice

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Anti-nociceptive effect of cimetidine in mice: the role of ATP-sensitive potassium channels

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Anti-nociceptive effect of cimetidine in mice: the role of ATP-sensitive potassium channels

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CD73-deficient mice are resistant to carcinogenesis.

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ژورنال

عنوان ژورنال: Diabetes & Metabolism Journal

سال: 2011

ISSN: 2233-6079

DOI: 10.4093/dmj.2011.35.3.219